Glycan epitopes have been collected by different authors and recorded in different ways in a few databases. Moreover, they are usually listed as independent entities despite their compositional similarity. GlyDyn’ is an exploration tool to visualise the relationships between epitopes based on monosaccharide composition.
This resource complies with the recommendations of the SNFG nomenclature for the representation of glycans.
This epitope network was produced using four different sources:
The network nodes are epitopes and two epitopes are connected when one is a substructure of the other. All nodes are labelled with epitope names. The epitopes called “unnamed” were not given names in the original sources.
Nodes have distinct shades of colour. Epitopes with the strongest shade are referenced in all four sources and appear in the foreground. Colour fades as a function of the number of source references decreases. In the background the lightest shade corresponds to nodes referenced in only one source.
How to start?
The following list of actions can be performed on the network: Hover over a node will prompt the epitope name and highlight neighbouring epitopes. Click on a node to see the epitope details. Double click on a node to highlight it and the nodes connected to it.
On the epitope panel, you can click on the target icon to center the graph on that epitope. Click on the link to a related epitope will move to that epitope Zoom over the graph with the “+” and “- “ signs.
[If you zoom in when centered on an epitope, the graph will expand around it]
Above a certain zoom level, epitope titles are automatically displayed for all the nodes.
The search button will fade all the nodes except the searched epitope.